/ · 1894 Brewer’s · G · Gis (g soft)
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i.e. Jesus. A corruption of Jesus or J. H. S. Ophelia says “By Gis and by St. Charity.” (Hamlet, iv. 5.)
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Entry taken from Dictionary of Phrase and Fable, edited by the Rev. E. Cobham Brewer, LL.D. and revised in 1895.