/ · 1894 Brewer’s · B · Belladonna (Italian, beautiful lady)
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This name was given to the Deadly Nightshade, from a practice once common among ladies of touching their eyes with it to make the pupils large and lustrous.
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Entry taken from Dictionary of Phrase and Fable, edited by the Rev. E. Cobham Brewer, LL.D. and revised in 1895.